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When used together: Antioxidants prevent the breakdown of collagen fibres Collagen improves the absorption of collagen peptides and supports natural production Skin appears brighter, smoother, and hydrated This synergy makes combining collagen with an antioxidant supplement for skin far more effective than using either alone

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ROS include, superoxide anion radical (O 2 ), peroxy radical (ROO ), hydrogen peroxide (H 2 O 2 ), singlet oxygen ( 1 O 2 ), perhydroxyl radical (HO 2 ) and extremely reactive OH, Table 1

In preclinical studies, carotene tended to maintain myocardial GSH levels and GPX activities and reduce oxidative stress in vitro and in vivo [143, 144]